hormone refractory prostate cancer definition
What is hormone-refractory prostate cancer
May 31 2020 · Answer In patients with serum testosterone castrate levels hormone-refractory prostate cancer is defined as 2-3 consecutive rises in prostate-specific antigen (PSA) levels obtained at intervals of
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Aug 11 2015 · Definition Prostate cancer that has become refractory that is it no longer responds to hormone therapy no longer responds to androgen ablation therapy.
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Some men receive hormone treatment as initial treatment but it is not considered to be curative even though PSA may go down. If a man is on hormone treatment and his PSA rises significantly from the nadir point it is known as hormone-refractory cancer recurrence. After prostate cancer recurrence is
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Prostate cancer is the most common cancer among men in the United States. For decades the cornerstone of medical treatment for advanced prostate cancer has been hormonal therapy intended to lower testosterone levels known as Androgen Deprivation Therapy (ADT). The development of hormone-resistant prostate cancer (now termed castration-resistant prostate cancer CRPC)
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Nov 19 2008 · Accordingly prostate cancer is referred to as a hormone sensitive disease. The problem that many many encounter though is that their disease will eventually progress despite hormone therapy and that condition is termed hormone refractory prostate cancer.
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Apr 10 2021 · Answer In patients with serum testosterone castrate levels hormone-refractory prostate cancer is defined as 2-3 consecutive rises in prostate-specific
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Castrate-sensitive castrate-resistant and hormone-refractory prostate cancer Castrate-sensitive prostate cancer (CSPC) means the cancer is being controlled by keeping the testosterone level as low Castrate-resistant prostate cancer (CRPC) means the cancer is still growing even when the
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Hormone therapy for prostate cancer is a treatment that stops the male hormone testosterone from being produced or reaching prostate cancer cells. Most prostate cancer cells rely on testosterone to help them grow. Hormone therapy causes prostate cancer cells to die or to grow more slowly.
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Hormone-refractory prostate cancer (HRPC) is cancer that is no longer helped by any form of hormone therapy. Men whose prostate cancer is still growing despite initial hormone therapy now have many more treatment options than they had even a few years ago.
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Apr 01 2008 · The hormone-refractory status is defined in a confirmed castrated man (who stopped any antiandrogen 6 wk earlier) by three consecutive prostate-specific antigen (PSA) increases above the nadir reaching at least more than 50 of the nadir.
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Hormone-refractory prostate cancer (HRPC) refers to prostate cancer that is no longer helped by any type of hormone therapy including the newer medicines.
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Hormone therapy for prostate cancer can block the production or use of androgens ( 4 ). Currently available treatments can do so in several ways reducing androgen production by the testicles. blocking the action of androgens throughout the body. block androgen production (synthesis) throughout the body.
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Jun 20 2017 · Castrate-Resistant Prostate Cancer HRPC Definition Prostate cancer that has become refractory that is it no longer responds to hormone therapy no
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Prostate cancer that is no longer stopped by low testosterone levels (less than 50 ng/mL) is called "castration resistant." Castration-resistant prostate cancer is defined by a rising PSA level and/or worsening symptoms and/or growing cancer verified by scans.
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Aug 01 1995 · The term "hormone-refractory" prostate cancer has evolved to include patients with a spectrum of diseases. As utilized in clinical trials of second-line hormonal therapies patients who have received one and as many as six different treatments have been included in the same study.
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Prostate Cancer Definition Prostate cancer is a disease in which cells in the prostate gland become abnormal and start to grow uncontrollably forming tumors. Description Prostate cancer is a malignancy of one of the major male glands. Along with the testicles and the seminal vesicles the prostate secretes the fluid that makes up semen. The
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ADT is the standard initial therapy in patients with recurrent disseminated prostate cancer. ADT can be achieved via bilateral orchiectomy or via gonadotropinreleasing hormone (GnRH) agonists and
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Abstract The belief that hormone‐refractory prostate cancer (HRPC) is a chemotherapy‐resistant disease has been effectively refuted by the results of two recent randomized phase III trials.
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Aug 24 2020 · Castrate-resistant prostate cancer is prostate cancer that stops responding to hormone therapy. Hormone therapy also called androgen deprivation
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Aug 11 2015 · Definition Prostate cancer that has become refractory that is it no longer responds to hormone therapy no longer responds to androgen ablation therapy.
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Abstract The belief that hormone‐refractory prostate cancer (HRPC) is a chemotherapy‐resistant disease has been effectively refuted by the results of two recent randomized phase III trials.
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Hormone Refractory Prostate Cancer Hormone refractory prostate cancer occurs when hormone therapy fails to the stop the growth of prostate cancer for any longer. Hormone refractory prostate cancer may occur a few months or even years after hormone therapy has been started.
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The biology of hormone refractory prostate cancer. Why does it develop Isaacs JT(1). Author information (1)Department of Oncology Johns Hopkins University School of Medicine Baltimore Maryland USA. Androgen ablation therapy has been an important modality for the treatment of disseminating prostatic cancer for nearly 60 years.
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ADT is the standard initial therapy in patients with recurrent disseminated prostate cancer. ADT can be achieved via bilateral orchiectomy or via gonadotropinreleasing hormone (GnRH) agonists and
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Cancer of prostate hormone refractory Carcinoma of prostate Hormone refractory prostate cancer Metastasis from malignant tumor of prostate Prostate cancer metastatic to eye Recurrent prostate cancer Clinical Information. A primary or metastatic malignant tumor involving the prostate gland. The vast majority are carcinomas.
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This page describes treatments for men whose prostate cancer is no longer responding so well to their first type of hormone therapy.You might hear this stage of cancer called hormone refractory hormone resistant androgen independent castration resistant or castrate resistant prostate cancer (CRPC).. Treatments for this stage of prostate cancer are often called second-line treatments as
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Hormone therapy for prostate cancer can block the production or use of androgens ( 4 ). Currently available treatments can do so in several ways reducing androgen production by the testicles. blocking the action of androgens throughout the body. block androgen production (synthesis) throughout the body.
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Feb 18 2021 · Hormone therapy attacks androgens that stimulate the growth of prostate cancer. A form of hormone therapy involves drugs called LHRH analogs or LHRH agonists that chemically block the production of androgens. Side effects of hormone therapy may include reduced libido abnormal growth or sensitivity of the breasts and hot flashes.
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The Hormone Refractory Prostate Cancer (HRPCa) Association was a volunteer organization of one hundred men with HRPCa their family members and their caregivers that existed from 1999 to 2016. Members were from all over the U.S. Canada and the globe.
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